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Thursday, February 14, 2008

Pervasive Developmental Disorders

Pervasive Developmental Disorders

INTRODUCTION
The term Pervasive Developmental Disorders was first used in the 1980s to describe a class of disorders. This class of disorders has in common the following characteristics: impairments in social interaction, imaginative activity, verbal and nonverbal communication skills, and a limited number of interests and activities that tend to be repetitive. The manual used by physicians and mental health professionals as a guide to diagnosing disorders is the Diagnostic and Statistical Manual of Mental Disorders (DSM). The DSM was last revised in 1994. In this latest revision, known as the DSM-IV, five disorders are identified under the category of Pervasive Developmental Disorders: (1) Autistic Disorder, (2) Rett’s Disorder, (3) Childhood Disintegrative Disorder, (4) Asperger’s Disorder, and (5) Pervasive Developmental Disorder Not Otherwise Specified, or PDDNOS.
Many of the questions parents and education professionals ask NICHCY have to do with children who have been diagnosed with “PDD.” Doctors are divided on the use of the term PDD. Many professionals use the term PDD as a short way of saying PDDNOS. Some doctors, however, are hesitant to diagnose very young children with a specific type of PDD, such as Autistic Disorder, and therefore only use the general category label of PDD. This approach contributes to the confusion about the term, because the term PDD actually refers to a category of disorders and is not a diagnostic label. The appropriate diagnostic label to be used is PDDNOS—Pervasive Developmental Disorder Not Otherwise Specified—not PDD (the umbrella category under which PDDNOS is found).

Accordingly, this Briefing Paper will use the term PDD to refer to the overall category of Pervasive Developmental Disorders and the term PDDNOS to refer to the specific disorder, Pervasive Developmental Disorder Not Otherwise Specified. The majority of this Briefing Paper will focus on PDDNOS. All of the disorders that fall under the category of PDD share, to some extent, similar characteristics. To understand how the disorders differ and how they are alike, it’s useful to look at the definition of each disorder. Therefore, before we begin our discussion of PDDNOS, let us look first at the definition of the general category PDD and its specific disorders.

THE PDD CATEGORY & ITS FIVE SPECIFIC DISORDERS
All types of PDD are neurological disorders that are usually evident by age 3. In general, children who have a type of PDD have difficulty in talking, playing with other children, and relating to others, including their family. According to the definition set forth in the DSM-IV (American Psychiatric Association, 1994), Pervasive Developmental Disorders are characterized by severe and pervasive impairment in several areas of development:
• social interaction skills;
• communication skills; or
• the presence of sterotyped behavior, interests, and activities.


The Five Types of PDD
(1) Autistic Disorder.
Autistic Disorder, sometimes referred to as early infantile autism or childhood autism, is four times more common in boys than in girls. Children with Autistic Disorder have a moderate to severe range of communication, socialization, and behavior problems. Many children with autism also have mental retardation.

(2) Rett’s Disorder.
Rett’s Disorder, also known as Rett Syndrome, is diagnosed primarily in females. In children with Rett’s Disorder, development proceeds in an apparently normal fashion over the first 6 to 18 months at which point parents notice a change in their child’s behavior and some regression or loss of abilities, especially in gross motor skills such as walking and moving. This is followed by an obvious loss in abilities such as speech, reasoning, and hand use. The repetition of certain meaningless gestures or movements is an important clue to diagnosing Rett’s Disorder; these gestures typically consist of constant hand-wringing or handwashing (Moeschler, Gibbs, & Graham 1990).

(3) Childhood Disintegrative Disorder.
Childhood Disintegrative Disorder, an extremely rare disorder, is a clearly apparent regression in multiple areas of functioning (such as the ability to move, bladder and bowel control, and social and language skills) following a period of at least 2 years of apparently normal development. By definition, Childhood Disintegrative Disorder can only be diagnosed if the symptoms are preceded by at least 2 years of normal development and the onset of decline is prior to age 10 (American Psychiatric Association, 1994).

(4) Asperger’s Disorder.
Asperger’s Disorder, also referred to as Asperger’s or Asperger’s Syndrome, is a developmental disorder characterized by a lack of social skills; difficulty with social relationships; poor coordination and poor concentration; and a restricted range of interests, but normal intelligence and adequate language skills in the areas of vocabulary and grammar. Asperger’s Disorder appears to have a somewhat later onset than Autistic Disorder, or at least is recognized later. An individual with Asperger’s Disorder does not possess a significant delay in language development; however, he or she may have difficulty understanding the subtleties used in conversation, such as irony and humor. Also, while many individuals with autism have mental retardation, a person with Asperger’s possesses an average to above average intelligence (Autism Society of America, 1995). Asperger’s is sometimes incorrectly referred to as “high-functioning autism.”

(5) Pervasive Developmental Disorder Not Otherwise Specified.
Children with PDDNOS either (a) do not fully meet the criteria of symptoms clinicians use to diagnose any of the four specific types of PDD above, and/or (b) do not have the degree of impairment described in any of the above four PDD specific types. According to the DSM-IV, this category should be used “when there is a severe and pervasive impairment in the development of social interaction or verbal and nonverbal communication skills, or when stereotyped behavior, interests, and activities are present, but the criteria are not met for a specific Pervasive Developmental Disorder, Schizophrenia, Schizotypal Personality Disorder, or Avoidant Personality Disorder” (American Psychiatric Association, 1994, pp. 77-78).

Diagnostic Criteria for Autistic Disorder
A. A total of six (or more) items from (1), (2), and (3), with at least two from (1), and one each from (2) and (3):
(1) qualitative impairment in social interaction, as manifested by at least two of the following: (a) marked impairment in the use of multiple nonverbal behaviors such as eye-to-eye gaze, facial expression, body postures, and gestures to regulate social interaction (b) failure to develop peer relationships appropriate to developmental level (c) a lack of spontaneous seeking to share enjoyment, interests, or achievements with other people (e.g., by a lack of showing, bringing, or pointing out objects of interest) (d) lack of social or emotional reciprocity.

(2) qualitative impairments in communication as manifested by at least one of the following: (a) delay in, or total lack of, the development of spoken language (not accompanied by an attempt to compensate through alternative modes of communication such as gesture or mime) (b) in individuals with adequate speech, marked impairment in the ability to initiate or sustain a conversation with others (c) stereotyped and repetitive use of language or idiosyncratic language (d) lack of varied, spontaneous make-believe play or social imitative play appropriate to developmental level.

(3) restricted repetitive and stereotyped patterns of behavior, interests, and activities, as manifested by at least one of the following: (a) encompassing preoccupation with one or more stereotyped and restricted patterns of interest that is abnormal either in intensity or focus (b) apparently inflexible adherence to specific, nonfunctional routines or rituals (c) stereotyped and repetitive motor mannerisms (e.g., hand or finger flapping or twisting, or complex whole-body movements) (d) persistent preoccupation with parts of objects

B. Delays or abnormal functioning in at least one of the following areas, with onset prior to age 3 years: (1) social interaction, (2) language as used in social communication, or (3) symbolic or imaginative play.

C. The disturbance is not better accounted for by Rett’s Disorder or Childhood Disintegrative Disorder. (APA, 1994, pp. 70-71)

Diagnostic Criteria for Rett’s Disorder
A. All of the following:
(1) apparently normal prenatal and perinatal development
(2) apparently normal psychomotor development through the first 5 months after birth
(3) normal head circumference at birth B. Onset of all of the following after the period of normal development
(1) deceleration of head growth between ages 5 and 48 months (2) loss of previously acquired purposeful hand skills between ages 5 and 30 months with the subsequent development of stereotyped hand movements (e.g., handwringing or hand washing) (3) loss of social engagement early in the course (although often social interaction develops later) (4) appearance of poorly coordinated gait or trunk movements (5) severely impaired expressive and receptive language development with severe psychomotor retardation. (APA, 1994, pp. 72-73)


Diagnostic Criteria for Childhood Disintegrative Disorder
A.
Apparently normal development for at least the first 2 years after birth as manifested by the presence of age-appropriate verbal and nonverbal communication, social relationships, play, and adaptive behavior.

B. Clinically significant loss of previously acquired skills (before age 10 years) in at least two of the following areas:
(1) expressive or receptive language (2) social skills or adaptive behavior (3) bowel or bladder control (4) play (5) motor skills

C. Abnormalities of functioning in at least two of the following areas:
(1) qualitative impairment in social interaction (e.g., impairment in nonverbal behaviors, failure to develop peer relationships, lack of social or emotional reciprocity)
(2) qualitative impairments in communication (e.g., delay or lack of spoken language, inability to initiate or sustain a conversation, stereotyped and repetitive use of language, lack of varied make-believe play)
(3) restricted, repetitive, and stereotyped patterns of behavior, interests, and activities, including motor stereotypes and mannerisms D. The disturbance is not better accounted for by another specific Pervasive Developmental Disorder or by Schizophrenia. (APA, 1994, pp. 74-75)

Diagnostic Criteria for Asperger’s Disorder
A.
Qualitative impairment in social interaction, as manifested by at least two of the following:
(1) marked impairment in the use of multiple nonverbal behaviors such as eye-to-eye gaze, facial expression, body postures, and gestures to regulate social interaction
(2) failure to develop peer relationships appropriate to developmental level
(3) a lack of spontaneous seeking to share enjoyment, interests, or achievements with other people (e.g., by a lack of showing, bringing, or pointing out objects of interest)
(4) lack of social or emotional reciprocity

B. Restricted repetitive and stereotyped patterns of behavior, interests, and activities, as manifested by at least one of the following:
(1) encompassing preoccupation with one or more stereotyped and restricted patterns of interest that is abnormal either in intensity or focus
(2) apparently inflexible adherence to specific, nonfunctional routines or rituals
(3) stereotyped and repetitive motor mannerisms (e.g., hand or finger flapping or twisting, or complex whole-body movements)
(4) persistent preoccupation with parts of objects

C. The disturbance causes clinically significant impairment in social, occupational, or other important areas of functioning.

D. There is no clinically significant general delay in language (e.g., single word used by age 2 years, communicative phrases used by age years).

E. There is no clinically significant delay in cognitive development or in the development of age-appropriate self-help skills, adaptive behavior (other than in social interaction), and curiosity about the environment in childhood.

F. Criteria are not met for another specific Pervasive Developmental Disorder, or Schizophrenia. (APA, 1994, p. 77)

REFERENCES
American Psychiatric Association. (1994). Diagnostic and statistical manual of mental disorders (4th ed.). Washington, DC: Author.

Autism Society of America. (1995). Asperger’s Syndrome information package. Bethesda, MD: Author.

Boyle, T. (1995). Diagnosing autism and other pervasive development disorders [excerpt from Autism: Basic information (3rd ed., pp. 6-7)]. Ewing, NJ: The New Jersey Center for Outreach & Services for the Autism Community, Inc. (COSAC).

Dalldorf, J. (1995). A pediatric view of the treatment options for the autistic syndrome. Chapel Hill, NC: Division TEACCH (Treatment and Education of Autistic and Related Communication Handicapped Children).

Mailloux, Z., & Lacroix, J. (1992). Sensory integration and autism. Torrance, CA: AYERS Clinic.

Moeschler, J., Gibbs, E., & Graham, J., Jr. (1990). A summary of medical and psychoeducation aspects of Rett Syndrome. Lebanon, NH: Clinical Genetics and Child Development Center.

Prizant, B. M., & Rydell, P. J. (1993). Assessment and intervention considerations for unconventional verbal behavior. In J. Reichle & D. Wacker (Eds.), Communicative alternatives to challenging behaviors (pp. 263-297). Baltimore, MD: Paul H. Brookes.

ZERO TO THREE: National Center for Infants, Toddlers, and Families. (1994). Diagnostic Classification of Mental Health and Developmental Disorders of Infancy and Early Childhood. Washington, DC: Author.


ORGANIZATIONS
Asperger Syndrome Coalition of the United States, Inc. (ASCU. S.), 2020 Pennsylvania Ave., NW, Box 771, Washington, DC 20006. Telephone: 1-866-427-7747. Web: www.asperger.org

Autism Society of America, 7910 Woodmont Avenue, Suite 300, Bethesda, MD 20814. Telephone: 1-800-328-8476. Web: www.autismsociety.org

International Rett Syndrome Association, 9121 Piscataway Road, Clinton, MD 20735. Telephone: 1-800-818-RETT; (301) 856-3334. Web: www.rettsyndrome.org

And try these Web Sites!
Autism Coalition: www.autismcoalition.com/
Autism Patient Center: www.patientcenters.com/autism/
Autism-PDD Resources Network: www.autism-pdd.net/
Division TEACCH: www.teacch.com/
Indiana Resource Center for Autism: www.iidc.indiana.edu/irca/
National Institute of Child Health and Human Development: www.nichd.nih.gov/publications/pubskey.cfm

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